abstract：BACKGROUND:This study was designed to investigate leptin levels in the fluid in ovarian endometriomas (OEs) and to compare the expression of leptin and its receptors (OBR) in ovarian tissue affected by endometrioma in infertile women to its expression in the normal ovarian tissue of fertile controls without endometrios...

journal_title：Journal of ovarian research

authors： Zendron C,Gonçalves HF,Cavalcante FS,Pereira TR,Evangelista A,Ramos CF,Oliveira MA

更新日期：2014-01-08 00:00:00

abstract：:Ovarian cystic tumors with a mural nodule are a rare entity. We report a case of a mural nodule of anaplastic spindle cell carcinoma in an ovarian mucinous cystic tumor of borderline malignancy. The patient was a 45-years-old Japanese woman who presented with an ovarian cyst. She suffered from mature cystic teratoma o...

journal_title：Journal of ovarian research

authors： Yamazaki H,Matsuzawa A,Shoda T,Iguchi H,Kyushima N

更新日期：2013-12-05 00:00:00

abstract：BACKGROUND:Epithelial ovarian cancer (EOC) is still a major gynecologic problem with poor 5 year survival rate due to distance metastases, despite routine surgery and chemotherapy. The precise underlying molecular mechanisms that trigger EOC migration and invasion are unclear. Recent studies suggest that the expression...

journal_title：Journal of ovarian research

authors： Zhang H,Wang Q,Zhao Q,Di W

更新日期：2013-11-26 00:00:00

abstract：BACKGROUND:Resistance to apoptosis is a major problem in ovarian cancer (OC) and correlates with poor prognosis. Osteoprotegerin (OPG) is a soluble secreted factor that acts as a decoy receptor for receptor activator of NF-κB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). OPG has be...

journal_title：Journal of ovarian research

authors： Lane D,Matte I,Laplante C,Garde-Granger P,Rancourt C,Piché A

更新日期：2013-11-23 00:00:00

abstract：OBJECTIVE:Recently, 14-3-3 zeta protein was identified as a potential serum biomarker of epithelial ovarian cancer (EOC). The goal of this study was to investigate the clinical potential of 14-3-3 zeta protein for monitoring EOC progression compared with CA-125 and HE4. DESIGN:Prospective follow-up study. SETTING:Uni...

journal_title：Journal of ovarian research

authors： Hatzipetros I,Gocze P,Koszegi T,Jaray A,Szereday L,Polgar B,Farkas N,Farkas B

更新日期：2013-11-15 00:00:00

abstract：:Ovarian hyperstimulation syndrome (OHSS) is a serious complication of controlled ovarian hyperstimulation (COH). The syndrome almost always presents either after hCG administration in susceptible patients or during early pregnancy. Despite many years of clinical experience, there are no precise methods to completely p...

journal_title：Journal of ovarian research

authors： Orvieto R

更新日期：2013-11-05 00:00:00

abstract：BACKGROUND:The polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine condition characterized by hyperandrogenism, hyperinsulinemia, insulin resistance and chronic anovulation. Regulation and interaction of a multitude of genes required for follicular development are found to be altered in PCOS. Micr...

journal_title：Journal of ovarian research

authors： Hossain MM,Cao M,Wang Q,Kim JY,Schellander K,Tesfaye D,Tsang BK

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:Although agonistic autoantibodies against type-1 angiotensin-II receptor (AT1-AA) are frequently detected in women with preeclampsia, the clinical significance of AT1-AA in association with epithelial ovarian cancer (EOC) has not been identified. METHODS:In an attempt to clarify this issue, we measured seru...

journal_title：Journal of ovarian research

authors： Song L,Zhang SL,Bai KH,Yang J,Xiong HY,Li X,Liu T,Liu HR

更新日期：2013-04-05 00:00:00

abstract：UNLABELLED: BACKGROUND:Women with polycystic ovary syndrome (PCOS) have higher risk for cardiovascular disease (CVD). Heart type fatty acid binding protein (HFABP) has been found to be predictive for myocardial ischemia.Wet ested whether HFABP is the predictor for CVD in PCOS patients, who have an increased risk of ca...

journal_title：Journal of ovarian research

authors： Cakir E,Ozbek M,Sahin M,Cakal E,Gungunes A,Ginis Z,Demirci T,Delibasi T

更新日期：2012-12-18 00:00:00

abstract：UNLABELLED: BACKGROUND:To investigate the 3.0-Tesla (3 T) magnetic resonance imaging (MRI) characteristics of primary adnexal lesions for discriminating benign from malignant lesions. METHODS:One hundred thirty-nine patients with pathologically proven primary adnexal masses referred for 3 T MRI assessment preoperativ...

journal_title：Journal of ovarian research

authors： Zhang H,Zhang GF,He ZY,Li ZY,Zhu M,Zhang GX

更新日期：2012-11-14 00:00:00

abstract：BACKGROUND:The polycystic ovary syndrome (PCOS) affects approximately 6-10% of women of reproductive age and is characterized by chronic anovulation and hyperandrogenism. However, a comprehensive understanding of the mechanisms that dictate androgen overproduction is lacking, which may account for inconsistencies betwe...

journal_title：Journal of ovarian research

authors： Wang F,Yu B,Yang W,Liu J,Lu J,Xia X

更新日期：2012-05-18 00:00:00

abstract：BACKGROUND:Survivin is an inhibitor of apoptosis and a regulator of mitotic progression. TP53 protein is a negative transcriptional regulator of survivin. The aim of our study was to evaluate the clinical significance of survivin expression in advanced stages ovarian cancer with respect to the TP53 status. METHODS:Sur...

journal_title：Journal of ovarian research

authors： Felisiak-Golabek A,Rembiszewska A,Rzepecka IK,Szafron L,Madry R,Murawska M,Napiorkowski T,Sobiczewski P,Osuch B,Kupryjanczyk J,Polish Ovarian Cancer Study Group (POCSG).

更新日期：2011-11-10 00:00:00

abstract：BACKGROUND:Glutathione peroxidase 3 (GPX3) is a selenocysteine-containing antioxidant enzyme that reacts with hydrogen peroxide and soluble fatty acid hydroperoxides, thereby helping to maintain redox balance within cells. Serum levels of GPX3 have been found to be reduced in various cancers including prostrate, thyroi...

journal_title：Journal of ovarian research

authors： Agnani D,Camacho-Vanegas O,Camacho C,Lele S,Odunsi K,Cohen S,Dottino P,Martignetti JA

更新日期：2011-10-22 00:00:00

abstract：BACKGROUND:Altered androgen hormone homeostasis and androgen receptor (AR) activity have been implicated in ovarian carcinogenesis but the relationship between AR expression in ovarian cancer and clinical outcome remains unclear. METHODS:In this study, the prognostic impact of AR expression was investigated using immu...

journal_title：Journal of ovarian research

authors： Nodin B,Zendehrokh N,Brändstedt J,Nilsson E,Manjer J,Brennan DJ,Jirström K

更新日期：2010-06-17 00:00:00

abstract：OBJECTIVES:Endometrioid carcinoma of the ovary is one of the most types of epithelial ovarian cancer associated to endometrioisis. Endometrioid tumors as well as endometriotic implants are characterized by the presence of epithelial cells, stromal cells, or a combination of booth, that resemble the endometrial cells, s...

journal_title：Journal of ovarian research

authors： Keita M,Bessette P,Pelmus M,Ainmelk Y,Aris A

更新日期：2010-01-28 00:00:00

abstract：OBJECTIVES:The ovarian tumor marker CA125 is expressed on human MUC16, a cell surface bound mucin that is also shed by proteolytic cleavage. Human MUC16 is overexpressed by ovarian cancer cells. MUC16 facilitates the binding of ovarian tumor cells to mesothelial cells lining the peritoneal cavity. Additionally, MUC16 a...

journal_title：Journal of ovarian research

authors： Goodell CA,Belisle JA,Gubbels JA,Migneault M,Rancourt C,Connor J,Kunnimalaiyaan M,Kravitz R,Tucker W,Zwick M,Patankar MS

更新日期：2009-06-18 00:00:00

abstract：OBJECTIVE:To review utilisation of elective embryo cryopreservation in the expectant management of patients at risk for developing ovarian hyperstimulation syndrome (OHSS), and report on reproductive outcome following transfer of thawed embryos. MATERIALS AND METHODS:Medical records were reviewed for patients undergoi...

journal_title：Journal of ovarian research

authors： Sills ES,McLoughlin LJ,Genton MG,Walsh DJ,Coull GD,Walsh AP

更新日期：2008-11-06 00:00:00